Molecular / Experimental Pathology Lab Lead

Company: Boehringer Ingelheim ( Learn More )

General Information
US-CT-Ridgefield
N/A
Graduate Degree
Full-Time
Not Specified
Not Specified
False
False
Job Description

Description:

Description\:

Molecular / Experimental Pathology Lab Lead-

In the Department of Cancer Immunology and Immune Modulation (CI&IM), we are currently looking for a highly motivated Molecular/Experimental Pathology Senior Principal Scientist/Principal Scientist to serve as a pathology laboratory lead within the Cancer Immunology Biomarker Team. The Biomarker group contributes to the discovery and identification of patient selection biomarkers as well as pharmacodynamic biomarkers in alignment with the respective project teams in research, preclinical and clinical development. Moreover the group is heavily involved in the characterization of the mode of action of novel immuno-oncology therapies. The Molecular / Experimental Pathologist will initiate, present and defend proposals and activities related to the mission of the Cancer Immunology Biomarker Team and the broader Cancer Immunology and Immune Modulation program. He/she will supervise a team of laboratory scientists and histologists, manage external collaborations and support the evaluation of digital pathology technologies. 

As an employee of Boehringer Ingelheim, you will actively contribute to the discovery, development and delivery of our products to our patients and customers. Our global presence provides opportunity for all employees to collaborate internationally, offering visibility and opportunity to directly contribute to the companies' success. We realize that our strength and competitive advantage lie with our people. We support our employees in a number of ways to foster a healthy working environment, meaningful work, diversity and inclusion, mobility, networking and work-life balance. Our competitive compensation and benefit programs reflect Boehringer Ingelheim's high regard for our employees

Duties & Responsibilities - Senior Principal Scientist\:

  • Lead an experimental pathology laboratory that performs histopathological and molecular characterization of cancer disease relevant models and human samples to understand the target-disease link

  • Establish and manage external collaborations with academic partners and CROs, including internal evaluation of new digital pathology technologies

  • Assumes responsibility for direct reports as needed including recruiting, managing, mentoring and developing scientific staff

  • Design and pre-clinically validate fit-for-purpose IHC and other tissue-based assays

  • Support the development of capabilities of the histopathology group, including multiplexed bright-field and immunofluorescence assays and quantitative image analysis using digital pathology platforms

  • Profile drug candidates to identify predictive and pharmacodynamic biomarkers to support development of cancer therapies

  • Provide scientific expertise for state-of-the-art oncologic pathology biomarkers for discovery and early clinical development

  • Coordinate effectively with other research teams and disciplines across the global Discovery Research Organization

  • Requirements - Senior Principal Scientist\:

  • DVM, MD and/or Ph.D. from an accredited institution with relevant post-doctoral experience

  • Seven-plus (7+) years of experience in one or more of the field listed below 

  • Industry experience is desirable

  • Expertise in anatomic pathology and demonstrated proficiency in interpreting and scoring IHC markers

  • Experience in experimental and digital pathology, cancer immunotherapy and biomarker research is desirable  

  • Demonstrated ability to work in multidisciplinary teams

  • Ability to plan, organize, troubleshoot, and present work independently and to show team leadership

  • Excellent communication and collaborative skills, and a track record of publications in the field

  • Appropriate level of understanding of applicable regulations

  • Ability to communicate effectively both orally and in writing in an inter-disciplinary environment

  • Leadership experience

  • Duties & Responsibilities - Principal Scientist\:

  • Lead an experimental pathology laboratory that performs histopathological and molecular characterization of cancer disease relevant models and human samples to understand the target-disease link

  • Establish and manage external collaborations with academic partners and CROs, including internal evaluation of new digital pathology technologies

  • Assumes responsibility for direct reports as needed including recruiting, managing, mentoring and developing scientific staff

  • Design and pre-clinically validate fit-for-purpose IHC and other tissue-based assays

  • Support the development of capabilities of the histopathology group, including multiplexed bright-field and immunofluorescence assays and quantitative image analysis using digital pathology platforms

  • Profile drug candidates to identify predictive and pharmacodynamic biomarkers to support development of cancer therapies

  • Provide scientific expertise for state-of-the-art oncologic pathology biomarkers for discovery and early clinical development

  • Coordinate effectively with other research teams and disciplines across the global Discovery Research Organization

  • Additional Specifics Regarding Duties & Responsibilities – Principal Scientist

  • Independently designs and performs scientific experiments with a predefined goal including developing new methodologies, protocols and or test procedures that contribute to core group/research goals and reflect expert knowledge; Direct and oversee experimental design and results of technicians and junior level scientists

  • Contributes to defining R&D team goals and collaborates with scientists within and outside functional area in achieving them; Assumes departmental responsibility for projects OR has ability to participate as representative on multiple project teams and contribute to defining expertise-related aspects of overall program goals

  • Prepares clear technical reports, publications and oral presentations. Independently communicate results in the form of reports and/ or presentations; Deliver updates to senior level management in context of overall project goals

  • Demonstrates an expertise in a specific project-relevant area OR technology; Provide guidance and expertise to advance specific projects OR evaluate and propose new technologies and concepts in support of multiple projects

  • Develops broad knowledge in field of expertise, including the ability to interpret current literature relevant to R&D projects, and visibility outside of functional area

  • Assumes responsibility for direct reports as needed including recruiting, managing, mentoring and developing scientific staff

  • Complies with all applicable regulations; Ensures that work performed in area of responsibility is conducted in a safe and compliant manner; Maintains proper records in accordance with SOPs and policies

  • Contributes to departmental administration; Demonstrates fiscal responsibility with respect to cost of experiments, technology, external collaborations, and travel

  • Requirements - Principal Scientist\:

  • DVM, MD and/or Ph.D. from an accredited institution with relevant post-doctoral experience

  • Five-plus (5+) years of experience in one or more of the field listed below 

  • Industry experience is desirable

  • Expertise in anatomic pathology and demonstrated proficiency in interpreting and scoring IHC markers

  • Experience in experimental and digital pathology, cancer immunotherapy and biomarker research is desirable  

  • Demonstrated ability to work in multidisciplinary teams

  • Ability to plan, organize, troubleshoot, and present work independently and to show team leadership

  • Excellent communication and collaborative skills, and a track record of publications in the field

  • Appropriate level of understanding of applicable regulations

  • Ability to communicate effectively both orally and in writing in an inter-disciplinary environment

  • Leadership experience

  • Eligibility Requirements\:

  • Must be legally authorized to work in the United States without restriction.

  • Must be willing to take a drug test and post-offer physical (if required)

  • Must be 18 years of age or older

  • Our Culture\:

    Boehringer Ingelheim is a different kind of pharmaceutical company, a privately held company with the ability to have an innovative and long term view.  Our focus is on scientific discoveries that improve patients' lives and we equate success as a pharmaceutical company with the steady introduction of truly innovative medicines.  Boehringer Ingelheim is the largest privately held pharmaceutical corporation in the world and ranks among the world's 20 leading pharmaceutical corporations.  At Boehringer Ingelheim, we are committed to delivering value through innovation.  Employees are challenged to take initiative and achieve outstanding results. Ultimately, our culture and drive allows us to maintain one of the highest levels of excellence in our industry.  Boehringer Ingelheim, including Boehringer Ingelheim Pharmaceuticals, Inc., Boehringer Ingelheim USA, Boehringer Ingelheim Animal Health USA, Inc., Merial Barceloneta, LLC and Boehringer Ingelheim Fremont, Inc. is an equal opportunity and affirmative action employer committed to a culturally diverse workforce - Minority/Female/Protected Veteran/Person with a Disability.  All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

    Boehringer Ingelheim is firmly committed to ensuring a safe, healthy, productive and efficient work environment for our employees, partners and customers. As part of that commitment, Boehringer Ingelheim conducts pre-employment verifications and drug screenings.

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